Scientist III

Company: Careerbuilder US
Location: Meriden
Posted on: January 12, 2021

Job Description:

Candidate will contribute directly to the Tech Transfer project between Client sites. As a member of the MTech and Quality teams at PSC, the candidate will provide right level of support to the transfer from sending site in terms of technical, documentation, and training support. Ensure the transferred process and analytical methods perform to expectations and demonstrate good consistency and robustness, and ensure the resulting operation added to the receiving site be sustainable, reliable, cost effective and compliant with HSE standards. Candidate will accomplish these tasks in a laboratory setting and through collaborations both internal and external. Responsibilities includes: Upstream Processing MTech: To assist in the development and execution of experiments in all upstream activities through SOPs and documented protocols. Duties will include molecular biology technics and methods, cell culture maintenance, virus expansion and preparation of seed and cell scale-up for bioreactor experiments. Secondary responsibilities will be to compile and analyze experimental data including the on-line and off-line sources and maintain database. Duties will include but not limited to operation and maintenance of bioreactors through execution of SOPs and protocols, data mining and analysis. Tertiary responsibilities will be to assist in basic laboratory analytical techniques. Duties will include SDS-PAGE, Western blots, SRID assay, pH meters, etc. The candidate is capable of identifying and troubleshooting the USP operation problems in small-scale bioreactors, participates in the process improvement program and provide support to the receiving site for mitigation studies and training. Downstream Processing MTech: Responsible for the development of seasonal and pandemic purification processes, as well as optimizing existing purification processes, and testing of new process and product for purity, yield and other biochemical characterizations. Involved in influenza program for the process scale-up, purification, process optimization, technology transfer, and process validation activities. Support tech transfer project with process/ product expertise and training for receiving site. Quality Department Responsible for training on, understanding, and following documented procedures which apply to QA and QC departments. Works with all QC Lab functions to support release testing of samples. Serve as technical support for analytical method assessment of sending site procedures (MTech and QC); support analytical method transfers from sending site to receiving site. Methodologies for the labs may include the following: molecular biology methods, microbiological/ virology methods and other biochemical testing methodologies supporting both licensed products and new vaccine projects. Prepares technical reports, summaries, protocols, and quantitative analyses. Uses professional concepts in accordance with company objectives to solve complex problems in creative and effective ways and other such duties and responsibilities as may from time to time be reasonably assigned. Job Requirements: Downstream Processing MTech: Responsible for the development of seasonal and pandemic purification processes, as well as optimizing existing purification processes, and testing of new process and product for purity, yield and other biochemical characterizations. Involved in influenza program for the process scale-up, purification, process optimization, technology transfer, and process validation activities. Support tech transfer project with process/ product expertise and training for receiving site.

Keywords: Careerbuilder US, Meriden , Scientist III, Other , Meriden, Connecticut